Cant decide when to harvest

EDIT2

Active Member
Hey, Ive been growing little plants on an off for a couple years now but currently i have a very small outdoor plant thats budding nicely but most of the leaves have turned yellow and died. The bud still looks good but i dont know if i should harvest early or let the bud grow some more. Will the growth be affected without the outside leaves?
Heres a pic

 
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