CGE sealed room co2 ?

Just finished setting up my CGE grow room and have question about the co2 set up the room is fully sealed no intake or exhaust and I'm running my co2 regulator on a cycle timer I know how long to leave it on so that the room fills but how often should I have it turn on if any of you are running a CGE set up it would be great if uu guys could help me out thanks
 
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