Right now I'd suggest v1 QB288s from HLG.
Ultra High Efficiency LED Boards for DIY. QB288 has 288pcs Samsung 561C for 5000K or Lumileds 2835HE for 3000K
horticulturelightinggroup.com
The sale is too good to pass up for boards like the QB120/QB132. Don't get me wrong, they're great boards (I primarily use 120s myself), and they can certainly make for an easier build (no heatsink), but the 288s have more headroom and at that price, why not? You could do anything from keeping it cheap and simple with 4 boards and an HLG-480 driver (they really put out more than 480 watts) to going for more spread and efficiency, with 6 boards and either a couple of 320 drivers or a single 600 (slightly more expensive than two 320s, but then you only have one driver to wire). Or cover the whole damn ceiling with them and mix and match drivers to hit your target power.
Personally, for a 4x4, I'd probably go with two 3-board 288 builds, each powered by an HLG-320H-54A. That provides the flexibility to adjust one side for unpredictable canopies, and having a second fixture in play is a nice redundancy if one fails (highly unlikely).