Please explain extended release as opposed to "controlled release and "continuous" release. My understanding is that there is some early work on varying blood plasma levels through changing release patterns in pills, establishing high levels as early as possible then perhaps changing that pattern as it may suit the patient's needs in a pre defined way.
But we know that there is a curve in plasma levels and that they begin to taper, depending upon the persons metabolism, his food intake etc, after what? 4 or 5 hours? Now extended release to my understanding simply keeps the plasma levels at a certain level by replenishing what has been metabolized. The pill might work for what? 8? 12 hours? Fine. Now how is that any different than "controlled release" I.E. keeping the entire dose from being absorbed at the same time, or continuous release which seems to mean the same thing.
I do not doubt that you have encountered more pharma opiates given the larger number of pharma users and the notion that if a doctor prescribes it, or if it is a pill, it must be somehow safer. I believe that Skuxx was responding to the fact that the OP was far from a virgin user, having been taking a pain medication that is usually only prescribed to patients who have established opioid tolerance. Taking this into account with the fact that we know the OP has 40 mg pills, it is most unlikely that he is liable to have a problem with a pill who's matrix was defeated. Furthermore notice I did suggest that it be titrated in some way just to be on the safe side.
OxyContin (oxycodone hydrochloride controlled-release), all are "continuous controlled" release. They do this by creating multiple layers of active and inactive ingredients which dissolve at different rates. Think of Oxycontin as Damascus steel, where there are layers of soft in between layers of hard. Chopping the pill will limit the continual release but it will still try to dissolve in layers. crushing the pill after removing the outer protective layer will allow the "instant and full effect", remember, 40mg with "instant and full effect" is dangerous and very possibly lethal to humans.
OxyER means it has more layers and a higher dosage. Regular Oxy @ 40mg is stronger than the ER version.
I was speaking on the extended release. and the deterx patent formulations..of which I'm very familiar
Canton, MA-— February 12, 2013—Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, today announced that it has received Notice of Allowance from the U.S. Patent and Trademark Office (USPTO) for its patent application
"Abuse-Deterrent Drug Formulation" US Patent Application Number 12/823,628. The Notice of Allowance is the USPTO’s official communication that the Company’s application has successfully completed examination and that a patent will be issued. This will be the third issued patent related to the DETERx
[SUP]®[/SUP] drug delivery technology.
The allowed patent claims cover the Company’s lead development program Oxycodone DETERx
[SUP]®[/SUP](COL-003), a tamper-resistant, extended-release oxycodone product utilizing its proprietary DETERx
[SUP]®[/SUP]technology. The Oxycodone DETERx
[SUP]®[/SUP] formulation was specifically designed to provide and preserve extended release of the active ingredient following the most common methods of product tampering employed by drug abusers (e.g., crushing, chewing, heating for IV injection, etc.). The product is currently in the final stage of clinical development and has been designated Fast Track Status by the FDA due to its potential to address the problem of prescription drug abuse, a major public health issue in the U.S.
http://www.collegiumpharma.com/press-releases/88-january-17-2013-collegium-pharmaceutical-announces-relocation-to-massachusetts
Tyedye, ask your doctor about Roxicontin if you have immediate pain which needs strong medication. Dont try to turn Oxycontin ER into Roxicontin.
ok.. So it is really amazing how these patents are working for these multi-billion $$ industry. I, myself, would like to chop and snort an Oxy like a champ but I never have nor have I mustard the reason.. The oxys work by using a dissolving "time-release", this will cause the oxy to dissolve and be absorbed over a long period of time. 
