"The God Molecule": 5-MeO-DMT - Natural and/vs Synthetic Forms

QUAD BREATH

Well-Known Member

Now how does the harvesting and consumption of bufotoxins impact the toad?

At this point in time (October 2018 the toads are classified as “least concern” on the IUCN Red List of Threatened Species (Hammerson & Santos-Barrera, 2004). Although this may be true, these assessments are from 2004, and is therefore very likely to be outdated. A new assessment about the toad’s population size is highly warranted given the attention the toad has received and the consumption of the toads’ bufotoxins worldwide.

Nevertheless, it is not old news that the amphibian population worldwide is declining. Actually, their global decline was first recognized in the early 1990s (Wake 1991). As of 2010, 32% of the world’s nearly 6600 amphibian species are threatened with extinction, 43% are experiencing declines and for another 22%, there are insufficient data (Stuart, Chanson et al. 2004). This phenomenon represents the Earth’s sixth mass extinction (Wake and Vredenburg 2008. That being said, there is no single cause to the global amphibian decline, rather there may be several contributing factors (Hayes, Falso et al. 2010). As outlined in the paper by Hayes and colleagues, there are three levels of possible factors for the amphibian decline.

The first level involves 1) death (or removal) of individuals and 2) reduced recruitment within a population. (Editors note: recruitment occurs when juvenile organisms survive to be added to a population, by birth or immigration, usually a stage whereby the organisms are settled and able to be detected by an observer. Source – Wikipedia

The second level involves 1) increased disease rate, 2) decrease in nutrition, 3) predation, 4) human exploitation 5) “other mortality”, which represent everything from the death of older individuals, incidental death, to catastrophic events.

Finally, the third level involves 1) atmospheric change, 2) environmental pollutants, 3) habitat loss, 4) invasive species, and finally 5) pathogens. These levels are also suggested to interact with one another.

It is not rocket science that the above-mentioned factors also have an impact on the toad. The increasing demand for the bufotoxins for inhalation has made the toad susceptible to not only ecological disturbance through the invasion of habitat and excessive milking, but also amphibian-trafficking and black-market dynamics. Additionally, according to herpetologist Robert Anthony Villa, the largest toads are most likely to be spotted and collected over smaller toads, and if you remove the biggest toads, you remove the population’s ability to sustain itself as the bigger toads have a lot of eggs (PsychedelicToday 2018). Moreover, based on studies on snakes, we know that 80% of snakes die if you catch them, move them to a different territory and let them go. Similarly, toads have an inner-GPS that they rely on, and if a toad is taken out of their territory for milking, and then set free elsewhere, they are very likely to die because they are either simply lost, could get run over by a car, or eaten by predators. The latter is more likely to successfully happen when the toad has been deprived of their main defense mechanism.

Along with that, Villa reports that the toad is very likely to be impacted negatively by pathogens, such as for example chytridiomycosis, which is exposed to them by people when they are collected for milking and can spread to the rest of the toad population. Additionally, as the surviving toads depend on the genetic variety of other populations to sustain themselves, the toads would inbreed themselves to extinction if there are no other populations to copulate with. Finally, keeping a toad as a pet, or many in large conservations for breeding, is a huge disservice to the toad as they do not do well in captivity, and due to the factors previously stated.

Given the circumstances, it seems to me that the harvesting and consumption of bufotoxins or so-called “toad medicine” is very much the case of the “double effect” principle; with a good act, comes a bad consequence. The aforementioned are all alarming factors that could very well lead toward population decline and so to extinction. This is all startling information that calls for action.




A discontinuation of “toad medicine” in favor of synthetic 5-MeO-DMT use can diminish the current unnecessary and excessive harassment of the Incilius Alvarius species. Switching from using toad bufotoxin to synthetic 5-MeO-DMT is better for many other reasons. First, synthetic 5-MeO-DMT does not contain a cocktail of other compounds and is therefore much safer to use. Likewise, it will be much easier for researchers to re-schedule and legalize a pure substance for medical use than a complex bufotoxin. Second, synthetic 5-MeO-DMT is not any different from “toad-medicine”. In fact, the argument that “toad-medicine” is better than synthetic is a claim that is drawn from personal experience and is not a good enough argument to extend to a generality.

Full Article: https://psychedelicstoday.com/2018/10/03/ethics-ecology-bufotoxins/
 
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Thundercat

Well-Known Member
I'm showing this stuff to my wife right now ;). She is a psychology student, and would really like to get into these avenues of research. We both have struggled at different points with depression and anxiety and would much rather explore natural(ish) ways of personal growth to overcome these things. I won't even be that person taking piles of pills for the rest of my life.
 

Gmz

Well-Known Member
i heard salvia gets rid of depression but can give you anxiety in heavier 50x or more extracts
Salvia imo feels like I just got in a really bad car wreck when I come back and can leave you questioning your entire reality, dmt can do that too but it seems more consistent with salvia. Never had any peaceful, loving or happy vibes from salvia like I've had from dmt.
 

QUAD BREATH

Well-Known Member
I'm showing this stuff to my wife right now ;). She is a psychology student, and would really like to get into these avenues of research. We both have struggled at different points with depression and anxiety and would much rather explore natural(ish) ways of personal growth to overcome these things. I won't even be that person taking piles of pills for the rest of my life.
That is awesome and great timing....as we enter a second psychedelic revolution. You sound like a very lucky guy having a wife that is interested in psychology and psychedelics.:-)

I'm really pro natural whenever possible as it helps you connect to nature, on a deeper level, and be more self sufficient. Good luck to you and your wife, it sounds really exciting.
 
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QUAD BREATH

Well-Known Member
i heard salvia gets rid of depression but can give you anxiety in heavier 50x or more extracts
I too have read that salvia can help some people with depression and other ailments. I think modern research is still ongoing but anecdotal evidence suggests that there is a place for this sacred medicine.

Here's a good article: http://www.maps.org/news-letters/v13n1/13118han.pdf

Depression washed away: https://erowid.org/experiences/exp_pdf.php?ID=57536&format=pdf
 
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QUAD BREATH

Well-Known Member
Therapeutic Use

Salvinorin A’s unusual pharmacology may help researchers to better understand and develop treatments for diseases characterized by hallucinations, including schizophrenia and Alzheimer’s.[10]

It could also be adapted for use in addiction therapy. A 2009 study found that when cocaine-addicted rats were exposed to Salvinorin A, their cocaine-seeking behavior (pushing a lever to self-administer the drug) became less frequent.[22] In part, this is due to the way in which κ-opioid receptors balance out and inhibit dopamine, the “reward” chemical released by cocaine.

High doses of vaporized Salvinorin A also seem to decrease interoception (our awareness of an emotional response to the body), severing the pleasure-seeking mechanism by which “body-after-drug” is negatively contrasted with “body-on-drug.”[23]

This makes Salvinorin A a powerful analgesic as well, and one without the respiratory complications of more conventional anesthetics. While studies on mice have shown the pain-relieving effects of Salvinorin A to be short-lived[24], the molecule has been used to develop longer-lasting analogs.[25][26] Anecdotal reports testify to Salvia’s use in treating headaches and arthritis pain.[27]

Salvia divinorum also shows promise in the treatment of depression, enhancing mood, relaxation, and self-awareness.[28][29] One 26-year-old woman who suffered from treatment-resistant depression since adolescence reported total remission through regular Salvia use. Specifically, she chewed 2-3 leaves (0.5-0.75g) three times a week. After six months, her depression was still in remission without any signs of relapse.[30]

Other potential therapeutic uses of Salvia include treating cancer [31] and perhaps even HIV/AIDS.

Above from: https://thethirdwave.co/psychedelics/salvia/
 
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QUAD BREATH

Well-Known Member

Experiences of ‘Ultimate Reality’ or ‘God’ Confer Lasting Benefits to Mental Health

04/23/2019

The encounter experiences, whether spontaneous or originated by a psychedelic, resulted in similar positive impact


People over the millennia have reported having deeply moving religious experiences either spontaneously or while under the influence of psychedelic substances such as psilocybin-containing mushrooms or the Amazonian brew ayahuasca, and a portion of those experiences have been encounters with what the person regards as “God” or “ultimate reality.” In a survey of thousands of people who reported having experienced personal encounters with God, Johns Hopkins researchers report that more than two-thirds of self-identified atheists shed that label after their encounter, regardless of whether it was spontaneous or while taking a psychedelic.

Moreover, the researchers say, a majority of respondents attributed lasting positive changes in their psychological health--e.g., life satisfaction, purpose and meaning--even decades after their initial experience.

The findings, described in a paper published April 23 in PLOS One, add to evidence that such deeply meaningful experiences may have healing properties, the researchers say. And the study’s design, they add, is the first to systematically and rigorously compare reports of spontaneous God encounter experiences with those occasioned, or catalyzed, by psychedelic substances.......

Among other key findings:
  • About 75 percent of respondents in both the non-drug and psychedelics groups rated their “God encounter” experience as among the most meaningful and spiritually significant in their lifetime, and both groups attributed to it positive changes in life satisfaction, purpose and meaning.
  • Independent of psychedelics use, more than two-thirds of those who said they were atheists before the experience no longer identified as such afterward.
  • Most participants, in both the non-drug and psychedelics groups, reported vivid memories of the encounter experience, which frequently involved communication with some entity having the attributes of consciousness (approximately 70 percent), benevolence (approximately 75 percent), intelligence (approximately 80 percent), sacredness (approximately 75 percent) and eternal existence (approximately 70 percent).
  • Although both groups reported a decreased fear of death, 70 percent of participants in the psychedelics group reported this change, compared with 57 percent among non-drug respondents.
  • In both groups, about 15 percent of the respondents said their experience was the most psychologically challenging of their lives.
  • In the non-drug group, participants were most likely to choose “God” or “an emissary of God” (59 percent) as the best descriptor of their encounter, while the psychedelics group were most likely (55 percent) to choose “ultimate reality.”


    Full Article: https://www.hopkinsmedicine.org/news/newsroom/news-releases/experiences-of-ultimate-reality-or-god-confer-lasting-benefits-to-mental-health
 
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QUAD BREATH

Well-Known Member
(3of6) 5-MeO-DMT, the God Molecule with James Oroc Part1
Martin Ball interviewing James Oroc, author of the book "Tryptamine Palace" which is about 5-MeO-DMT.

Oroc's first experience with 5-MeO was the synthetic version ordered online when it was widely available. Originally, Oroc was a staunch atheist and @ 5:30 said he came into contact with God consciousness. Being a hardcore atheist this was a surprise to him and was the beginning where, in his own words, his worldview started crumbling down :eek: :shock: lol .........................
 
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QUAD BREATH

Well-Known Member
Upcoming World Bufo Alvarius Congress Looks to Nurture Global 5-MeO-DMT Community
Posted by Wesley Thoricatha | Jul 16, 2019 |



You hear of many different substances referred to as “the strongest psychedelic on the planet”, and while that moniker is subjective, 5-MeO-DMT is certainly in the running. Whether you are smoking the secretion of the Bufo alvarius Sonoran Desert Toad which contains 5-MeO-DMT , or the pure synthetic version, this “god molecule” is known to reliably grant an incredibly intense “ego-death” experience where one dissolves into unity with the totality of existence.

Aside from the intensity of the journey that 5-MeO-DMT provides, what makes it unique is the fact that it does not have a historical lineage of traditional use that we are aware of. Hence, modern practitioners are left with the challenge and opportunity of creating a new contemporary global tradition around 5-MeO-DMT and the Bufo alvarius toad. At the forefront of this movement to unify global practitioners, codify best practices, and nurture this burgeoning scene are Rak Razam and Mario Garnier, who are putting on the World Bufo Alvarius Congress (WBAC) later this month in Mexico City. We spoke recently with Rak and Mario about this event, its history, and why it’s important for the diverse 5-MeO community to coalesce and support each other.


https://psychedelictimes.com/world-bufo-alvarius-congress/



https://www.wbac.info/
 
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