Using Colchicine

Anything you know will help others new to this type of "super growing"

ok.... well i have been checkin out this drug called cholchicine which mutates a plant into a polyploid during its seed stage by soaking the seed in a distiled water, cholchicine solution of .10% cholchicine. This process mutates the seedlings (by the way if any survive) into this "golden" super strain. A polyploid is a state different from most organisms in the fact that it has more than 2 sets of homologous chromosomes. and what i take from this is that the plant mutates into a male/ female plant at the same time. The advantages to my knowledge "only because of explorations of other people" has been a better, strong, and bulkier plant. Also it is said that many people had the flowering process slowed down. to me this is ok only if the end product is better, meaning FUEGO BUD! so i started this thread to hear from ones tries and either successes or failures. AND to learn and teach. if any of this is wrong in your opinion please tell me so i also could better understand more about this i guess undercover growing method. thanx

This has been a method around for a LONG time. I remember it from, well, let's just say it was a long time ago. It does what you say, though it does have a down side, at least for the plant treated with it for the 1st generation. The cholchicine contained in the plant can be fatal if ingested. 2nd generation plants are safe, and of increased vigor.

yeah...i found that earlier today on another research spree lol so does this mean i can use clones if not what would be concidered 2nd generation.

clones would be a bit of a gray area, at least for 1st generation
at some point in the clone chain, the level is going to become non-existent
not sure where that point is

This turned to be a pretty interesting idea when you mentioned clone. From my memory, this used to be primarily used for breeding. The polploid parents would produce a more vigorous 2nd generation, or at least that is what I remember.

The thought of getting a polyploid clone that is free of the colchicine, well I'm not sure, but it sounds like you might get a very vigorous plant.

Thanks for bringing up the topic and +rep to you.

growone said:

This turned to be a pretty interesting idea when you mentioned clone. From my memory, this used to be primarily used for breeding. The polploid parents would produce a more vigorous 2nd generation, or at least that is what I remember.

The thought of getting a polyploid clone that is free of the colchicine, well I'm not sure, but it sounds like you might get a very vigorous plant.

Thanks for bringing up the topic and +rep to you.

Click to expand...

So are you saying use a polyploid male and female then pollinate?

Does it affect genetics? I wouldn't think the offspring would be affected.

If that stuff is toxic say it has .001% in the plant matter from the original mutated plant, the clone will have a little bit less, then if you grow it out and take another clone it will have even less...

But IDK if I would really want to chance it.

I had a polyploid cola on my plant that was due to a severe nute burn.

lol...When I was in college my genetics teacher mentioned this in her lecture. Apparently students back in the 70's kept stealing it from the labs to use on their plants.

I'm sure there's some stuff about it in my genetics book. I'll look into it and post later. I know that it has something to do with turning what would normally be one bud into two. That's probably the whole polyploid thing that you're talking about...

Isn't cholchicine a carcinogen?

cholchicine is mucho toxic - I don't think it is carcinogenic, used as medicine in the treatment of gout
in very dilute form that is
as far as what is does, and this from memory - it doubles up the chromosomes or some such thing
it's been used in plant breeding for quite some time
on the clone issue and toxic amounts - not planning on trying it anytime soon
but it was interesting, in what you might get for a clone that was treated with it

ok well i looked into it last night so this might not be exactly right but ok... the cholchicine is a systemic which i alreayd new meaning it stays in a plant ( including clones) and like all chemicals it has a half life and i didnt look it up..But in a few trials of others they said once treated doooo nooot smoke bud off the originaly treated plants. also after you treat a plant it IS A MUTATED PLANT so the odviously the clones will also be mutated because it is the same plant. so i think i am going to try this in a few months and will use the clones to continue the mutated strain instead of someone who said polenation, i think by the time the clone buds i will be safe. if not thats what a hospital is for lol.

this is a brave road you're going down
if you do proceed, and survive, please post results

yeah ill start me a nice little grow journal and message you. i cant wait and well if i ever have gout lol i guess it will help

hi guys I take colchicine for my gout 1mg per tab i can take about 6 of these a day any more and you get the shits so its use to remove uric acid from my body so why would the smoke be bad for you?
interesting tread

maybe there is a safe colchicine for humans to ingest in small amounts.

upwind said:

hi guys I take colchicine for my gout 1mg per tab i can take about 6 of these a day any more and you get the shits so its use to remove uric acid from my body so why would the smoke be bad for you?
interesting tread

Click to expand...

that is exactly the reason - it's therapeutic in small amounts - deadly in larger amounts

growone said:

that is exactly the reason - it's therapeutic in small amounts - deadly in larger amounts

Click to expand...

I second that. It's all about how much you take. Even water is toxic if you drink too much

lmao your right but were dealin with the pure shit lmao and its pretty potent stuff lmao

im a firm belive in clones keep exact genitics of the mother so in my opinion thats why u need to pollenate a mutated pland to get seed to grow a smokable child plant because although it has its mother and fathers traits its also got its own dna as with any new life and no amount of cloning will loose the mutated cells but i could be completly wrong