Looks like pests on the middle leaves and a nitrogen or sulfur def on the bottom ones.
Nitrogen (N) - Restricted growth of tops and roots and especially lateral shoots. Plants become spindly with general chlorosis of entire plant to a light green and then a yellowing of older leaves which proceeds toward younger leaves. Older leaves defoliate early.
Sulfur (S) - Resembles nitrogen deficiency in that older leaves become yellowish green and the stems become thin, hard, and woody. Some plants show colorful orange and red tints rather than yellowing. The stems, although hard and woody, increase in length but not in diameter.