Depends what it is you're starting with and what you want to do. I frequently read people recommending 15, 20, even 30 percent perlite or more... to be added to bagged potting mix that already has perlite in it to begin with.
So what mix is it that you're starting with and whats in it?
I usually use FF Ocean Forest or Sunshine Adv. Mix #4 as a base and I personally think that both of these contain plenty of perlite as is. Instead I just add coco coir to the Ocean Forest. The reason I am weary of adding tons of perlite is that perlite is totally inert, non-nutritive and has no cation exchange capacity. If you use too much it can collect and form pockets throughout your mix where plant roots wont want to grow.
Coir fibers, earthworm castings, vermiculite, pumice, are all alternatives that will help keep soil aerated... the former have the added benefits of being sources of carbon\organic matter which microbes can live on and have or can hold onto nutrients.