60-80% coco to 20-40% perlite depending on how often you want to water. some just use straight coco which is decent medium that can usually go a couple days without watering. But I don't mind watering daily (i use drip irrigation) so I mix a healthy amount of perlite in there to give the roots plenty of air to breathe.
Coco is amazing. It can be hand watered to achieve results better than soil, or irrigated hydoponically for hydroponic results. It's very forgiving, and buffers easily.
Using unamended coco will require a hydroponic nutrient solution no matter how you water it. Dyna gro is great and affordable. Many members on here swear by it, myself included.