If you have forced air heat, there are two kinds of ducts. Hot air ducts, and cold air returns (which allow air to leave and keep it flowing). Ducts are just things you can go look at from the basement. You can touch them and see where they go and what they must be there for. If you want to modify them to go or do something else, there is ductwork material available at hardware and hvac stores. Otherwise I don't understand your question.
I wouldn't modify any ductwork though. It was probably set up just the way it is for very good reasons, and taking the entire place's floorplan into consideration.