Making pure Delta9-THC oil

mattman said:

First of Mr. Angry pants, the above quote is not clear on whether or not you have studied a particular branch of chemistry. I was simply asking if you had taken organic chemistry, maybe I was leading my question to more ideas, but thats out of the question now.

2nd and lastly, I never said anything about acetone. I will go on to say that i have had 4 years of chemistry including organic and am currently running a research project on plant alkaloids and phenols to understand more about their reaction on the nervous system. I will also go on to say that anytime my professors or myself handle ANY solvent that we wear the proper gloves and eyewear. This is my last post and view on your thread, although a great topic, I'll take my brain elsewhere.

-Mattman

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Finshaggy said:

SOOOO I don't care if it was clear on that. You asked about organic chemcistry and I told you if you raed more that I did not do organic.

YOU QUOTED ME ON ACETONE DUMB ASS. The quote you pulled talked about Acetone, and RIGHT AFTER you said your little thing about Ochem.

I'm glad that you guys wear gloves. I dump Acetone on my hands JUST to feel the evaporation. It's a crazy sensation. AND IT'S COMPLETELY SAFE. NOT SUGGESTING YOU DO THAT, but it is safe for what I said to use it for in the experiment. AND I'm pretty sure the experiment says you can use alcohol or water too. So Idk why everyone is so caught up on Acetone and Danger of solvents. Go use a water method if it's gonna be such a big deal to you.

And I'm not angry, I'm just replying.

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mattman said:

Ill assume that you won't be on this planet that much longer

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THC acetate has twice the potency of THC. On the Adams scale THC 7.3, while its acetate = 14.6. Furthermore, there is a 25% increase in weight after adding the acetate structure. The effect of the acetate is more spiritual and psychedelic than that of the ordinary product. The most unique property of this material is that there is a delay of about thirty minutes before its effects are felt.
...
THC is converted to THC acetate by refluxing for two hours with acetic anhydride.

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Preparation of 1-Acetoxy-7 ,8,9,1 O-tetrahydro-3-(1-methylhexyloxy)6,6,9-trimethyl-6Hdibenzo[b,d]pyran by Bernard Loev of Broomall, Pa. July 18,1973

A solution of 1.0 g. of 1-hydroxy-7,8,9,10-tetrahydro-3-(1-methylhexyloxy)-6,6,9-trimethyl6H-dibenzo[b,d]pyran in 20 mL. of acetic anhydride containing 0.5 g. of sodium acetate is refluxed for 5 hours. The excess anhydride is evaporated in vacuo and the residue is dissolved in water and extracted with ether. The extract is washed with water

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Preparation of dl-trans-1-Acetoxy-3-(1 ',1 'dimethylheptyl)-6,6-dimethyl-6,6a, 7 ,8,10,1 Oa-hexahydro-9Hdibenzo[b, d]pyran -9-one: By Robert A. Archer of Indianapolis, IN Louis Lemberger of Indianapolis, IN February 17,1976

A mixture of 500 mg. of dl-trans-1-hydroxy-3-(1',1 'dimethylheptyl)-6,6-dimethyl-6,6a,7 ,8,10,1 Oa-hexahydro-9Hdibenzo[b,d]pyran-9-one, 5 mL. of acetic anhydride, and 5 mL. of pyridine was stirred under an inert atmosphere for 16 hours. The mixture was then poured onto ice and extracted with ethyl acetate. The ethyl acetate extract was washed with 1 N HCI and saturated sodium chloride solution, dried over anhydrous sodium sulfate and evaporated in vacuo to give 450 mg. of dl-trans-1-acetoxy-3-(1',1 '-dimethylheptyl)-6,6-dimethyl-6,6a, 7 ,8,10,1 Oa-hexahydro-9H -dibenzo-[b,d]pyran-9-one as a viscous oil: Rf =0.33(Silica gel, 10% Ethyl acetate:benzene): IR (CHCI3) 5.62, 5.80, and 8.28 mu; molecular ion at m/e 414.
As previously mentioned, compounds represented by Formula IV above have the ability to produce bronchodilitation in humans and can alleviate bronchial asthma in man. Bronchial asthma, including both extrinsic or allergic asthma and intrinsic or infective asthma, is characterized by recurrent paroxysms of dyspnea associated with a characteristic type of wheezing caused by obstruction of the flow of air in the smaller bronchi and bronchioles. In more severe attacks, trapping of air in the alveoli may occur, completely obstructing the airways, which event may result in death. Drugs represented by Formula IV above appear to act to alleviate asthmatic symptoms by relaxing bronchial smooth muscle thereby increasing the passage of air from the lung. They may also act, in part, by a central mechanism relieving anxiety, a major companent of this disease. Source: Archer 1978; Johnson 1980

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A portion (23 .0 g) of the hexane extract was subjected to fractional distillation under reduced pressure (vacuum, 0.1-0.2 mmIHg). The temperature was raised slowly to 160° C. where a small amount of material (<1 g) was collected and left separate. The major fraction (10.1 g) was collected between 170 and 180 ° C. GC analysis of this fraction showed 72.66% THC concentration.
A second portion (25.0 g) of the hexane extract was subjected to fractional distillation under similar conditions as the first portion. The major fraction collected between 170-180° C. weighed ll.6 g and had a THC concentration of 73.62%.
A third portion (25.0 g) of the hexane extract was subjected to fractional distillation under similar conditions to the previous portions. The major fraction containing THC weighed 10.2 g and had a THC concentration of 73.72%.
The three major fractions obtained from the above three distillations were combined and analyzed. The analysis showed the concentration of THC to be 70.31 %. The mixture (28.9 g) was subjected to fractional distillation, again under similar conditions. The temperature was raised slowly to 135 ° C. under vacuum (0.1-0.15 mmHg) and the fractions collected were kept aside. The major THC containing fraction was collected at 140-160° C. and 0.05-0.06 mmIHg. The fraction weight was 18.4 g and the THC content was 92.15%. Source: Elsohly 2002

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Given the world wide ready availability of marijuana, it is somewhat difficult to produce a viable argument for making CsA's of cannabinoids. However, ten years ago (197 an attempt to produce CsA's from cannabis extracts was encountered in the Jacksonville, Florida area. In this case a concentrated extract of cannabis had been obtained by a soxhlet extraction. The extract had been acetylated with acetic anhydride, and in the final step, the excess acetic anhydride removed by distillation (reference is unretrievable due to its appearance in an underground periodical). The product contained neither quantities of nonderivatized cannabinoid nor any identifiable plant fragments. Since this single instance, no acetalaced cannabinoid samples have been reported by a DEA laboratory. Therefore, this instance is assumed to represent an isolated occurrence and as such, will serve to terminate our discussion of cannabinoid CsA's.

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Cali chronic said:

Becareful.... Here is a Youtube i got from an earlier post in another area. IF you are not sure who Rick Simpson is Google him with the word Cannabis
http://www.youtube.com/watch?v=KZXGH6mYr3Y

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ddimebag said:

I have some background in organic chemistry. Pouring acetone on your hands and letting it evaporate is dangerous. Don't do it anymore. Acetone is poisonous, no matter what you seem to think, and permeates through the skin very easily. It's fine to use for extractions as long as you are sure it is pure (get lab grade or at least pharmacy grade) and as long as you evaporate ALL OF IT! (or decant, like you do, just make sure you take a little bit of the ether layer with it, so you are sure all the acetone is gone.) Once you have your extract as pure as you want it, it would be a good idea to vacuum dry it, to get rid of any remaining solvent.

I think the best bet for you is butane hash oil, that you can isomerise if you want. Don't have the time to explain it step by step, but you can just look that up or pm me. BHO is already concentrated enough to blow your mind...if you isomerise that, then you should have some crazy potent smoke...

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Finshaggy said:

I make sure it's pure, and I evaporate all of it.


OUr body make absorb acetone through the skin in small amounts, but it has a good system of getting rid of acetone.
Our bodies can sweat it, piss it, and breathe it out, at a pretty quick rate.
Quicker than it can absorbed into a little patch on your arm

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ddimebag said:

I have some background in organic chemistry. Pouring acetone on your hands and letting it evaporate is dangerous. Don't do it anymore. Acetone is poisonous, no matter what you seem to think, and permeates through the skin very easily. It's fine to use for extractions as long as you are sure it is pure (get lab grade or at least pharmacy grade) and as long as you evaporate ALL OF IT! (or decant, like you do, just make sure you take a little bit of the ether layer with it, so you are sure all the acetone is gone.) Once you have your extract as pure as you want it, it would be a good idea to vacuum dry it, to get rid of any remaining solvent.

I think the best bet for you is butane hash oil, that you can isomerise if you want. Don't have the time to explain it step by step, but you can just look that up or pm me. BHO is already concentrated enough to blow your mind...if you isomerise that, then you should have some crazy potent smoke...

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