smokinskins
New Member
wondering how they make fun stuff. nothing specific, i wondering about any of it.
Anyone Got a Good Recipe for Anything? Im Curious How Stuffs Made(any of it)
- Thread starter smokinskins
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Playing With PEA's
New Member
My geuss is that this guy wants to know how things are synthesized. He is also asking someone to give him a rundown on a synthesis. This is a 'fun' chemical known as GANESHA. 
A solution of 15.4 g 2,5-dimethoxy-3,4-dimethylbenzaldehyde (check PIHKAL for the preparation) in 50 mL nitroethane was treated with 3 g anhydrous ammonium acetate and heated on the steam bath for 12 h. The excess nitroethane was removed under vacuum, and the residual oil was diluted with a equal volume of MeOH. There was the slow generation of deep red cottage-cheese-like crystals which were removed by filtration and air-dried to constant weight (9.3 g) with a mp 71-74 °C. Recrystal-lization from MeOH (10 ml/g) gave an analytical sample of 1-(2,5-dimethoxy-3,4-dimethylphenyl)-2-nitropropene with a mp of 82 °C sharp. Anal. (C13H17NO4) C,H,N. The NMR spectra (in CDCl3) and CI mass spectrograph (MH+ = 252) were proper.
To a suspension of 3.3 g LAH in 200 mL refluxing THF, well stirred and maintained under an inert atmosphere, there was added 4.2 g 1-(2,5-dimethoxy-3,4-dimethylphenyl)-2-nitropropene in 25 mL THF. The mixture was held at reflux for 48 h. After cooling, 3.3 mL H2O was added cautiously to decompose the excess hydride, followed by 3.3 mL 15% NaOH and finally another 10 mL H2O. The inorganic solids were removed by filtration, and washed with additional THF. The combined filtrate and washes were stripped of solvent under vacuum, and the residue (4.7 g of a deep amber oil) dissolved in dilute HCl. This was washed with CH2Cl2 (3x75 mL), then made basic with 5% NaOH and extracted with CH2Cl2. Removal of the solvent under vacuum yielded an amber oil that was distilled (105-115 °C at 0.4 mm/Hg) to give 1.2 g of a white oil. This was dissolved in 8 mL IPA, neutralized with 15 drops of concentrated HCl, and diluted with 250 mL anhydrous Et2O. After a period of time, there was a spontaneous appearance of white crystals which were removed by filtration, Et2O washed, and air dried. Thus was obtained 1.0 g of 2,5-dimethoxy-3,4-dimethylamphetamine hydrochloride (GANESHA) with a mp of 168-169 °C. This was not improved by recrystallization from either EtOAc or nitroethane. Anal. (C13H22ClNO2) N.
A solution of 15.4 g 2,5-dimethoxy-3,4-dimethylbenzaldehyde (check PIHKAL for the preparation) in 50 mL nitroethane was treated with 3 g anhydrous ammonium acetate and heated on the steam bath for 12 h. The excess nitroethane was removed under vacuum, and the residual oil was diluted with a equal volume of MeOH. There was the slow generation of deep red cottage-cheese-like crystals which were removed by filtration and air-dried to constant weight (9.3 g) with a mp 71-74 °C. Recrystal-lization from MeOH (10 ml/g) gave an analytical sample of 1-(2,5-dimethoxy-3,4-dimethylphenyl)-2-nitropropene with a mp of 82 °C sharp. Anal. (C13H17NO4) C,H,N. The NMR spectra (in CDCl3) and CI mass spectrograph (MH+ = 252) were proper.
To a suspension of 3.3 g LAH in 200 mL refluxing THF, well stirred and maintained under an inert atmosphere, there was added 4.2 g 1-(2,5-dimethoxy-3,4-dimethylphenyl)-2-nitropropene in 25 mL THF. The mixture was held at reflux for 48 h. After cooling, 3.3 mL H2O was added cautiously to decompose the excess hydride, followed by 3.3 mL 15% NaOH and finally another 10 mL H2O. The inorganic solids were removed by filtration, and washed with additional THF. The combined filtrate and washes were stripped of solvent under vacuum, and the residue (4.7 g of a deep amber oil) dissolved in dilute HCl. This was washed with CH2Cl2 (3x75 mL), then made basic with 5% NaOH and extracted with CH2Cl2. Removal of the solvent under vacuum yielded an amber oil that was distilled (105-115 °C at 0.4 mm/Hg) to give 1.2 g of a white oil. This was dissolved in 8 mL IPA, neutralized with 15 drops of concentrated HCl, and diluted with 250 mL anhydrous Et2O. After a period of time, there was a spontaneous appearance of white crystals which were removed by filtration, Et2O washed, and air dried. Thus was obtained 1.0 g of 2,5-dimethoxy-3,4-dimethylamphetamine hydrochloride (GANESHA) with a mp of 168-169 °C. This was not improved by recrystallization from either EtOAc or nitroethane. Anal. (C13H22ClNO2) N.
smokinskins
New Member
My geuss is that this guy wants to know how things are synthesized. He is also asking someone to give him a rundown on a synthesis. This is a 'fun' chemical known as GANESHA.
A solution of 15.4 g 2,5-dimethoxy-3,4-dimethylbenzaldehyde (check PIHKAL for the preparation) in 50 mL nitroethane was treated with 3 g anhydrous ammonium acetate and heated on the steam bath for 12 h. The excess nitroethane was removed under vacuum, and the residual oil was diluted with a equal volume of MeOH. There was the slow generation of deep red cottage-cheese-like crystals which were removed by filtration and air-dried to constant weight (9.3 g) with a mp 71-74 °C. Recrystal-lization from MeOH (10 ml/g) gave an analytical sample of 1-(2,5-dimethoxy-3,4-dimethylphenyl)-2-nitropropene with a mp of 82 °C sharp. Anal. (C13H17NO4) C,H,N. The NMR spectra (in CDCl3) and CI mass spectrograph (MH+ = 252) were proper.
To a suspension of 3.3 g LAH in 200 mL refluxing THF, well stirred and maintained under an inert atmosphere, there was added 4.2 g 1-(2,5-dimethoxy-3,4-dimethylphenyl)-2-nitropropene in 25 mL THF. The mixture was held at reflux for 48 h. After cooling, 3.3 mL H2O was added cautiously to decompose the excess hydride, followed by 3.3 mL 15% NaOH and finally another 10 mL H2O. The inorganic solids were removed by filtration, and washed with additional THF. The combined filtrate and washes were stripped of solvent under vacuum, and the residue (4.7 g of a deep amber oil) dissolved in dilute HCl. This was washed with CH2Cl2 (3x75 mL), then made basic with 5% NaOH and extracted with CH2Cl2. Removal of the solvent under vacuum yielded an amber oil that was distilled (105-115 °C at 0.4 mm/Hg) to give 1.2 g of a white oil. This was dissolved in 8 mL IPA, neutralized with 15 drops of concentrated HCl, and diluted with 250 mL anhydrous Et2O. After a period of time, there was a spontaneous appearance of white crystals which were removed by filtration, Et2O washed, and air dried. Thus was obtained 1.0 g of 2,5-dimethoxy-3,4-dimethylamphetamine hydrochloride (GANESHA) with a mp of 168-169 °C. This was not improved by recrystallization from either EtOAc or nitroethane. Anal. (C13H22ClNO2) N.
whoa ive never heard of ganisha! what is it? any idea how L or E is made?
Playing With PEA's
New Member
It's a very pleasent experience, very good PEA. It's a relative of the 2C compounds.
Yes, I do.
Yes, I do.
smokinskins
New Member
what like 2cI? i saw some at a show one time but i didnt try that one. this stuff is complicated and i dont have equiptment but id like to still like to see what goes into stuff
Playing With PEA's
New Member
I'm pretty sure most drug syntheses are over your head.
smokinskins
New Member
yeah but phil me in
Anonymiss1969
Active Member
Here you go:
http://lmgtfy.com/?q=how+to+make+LSD
http://lmgtfy.com/?q=how+to+make+ecstasy
Good luck!
http://lmgtfy.com/?q=how+to+make+LSD
http://lmgtfy.com/?q=how+to+make+ecstasy
Good luck!
Playing With PEA's
New Member
Aahh, why'd you do that?!?
thehairyllama
Well-Known Member
HAHA I never seen that shit. LMGTFY haha
thehairyllama
Well-Known Member
Thanks FDD Ive been looking for that for centuries.
silentzombie
Active Member
To the OP.
Take an organic chemistry class. Actually, take a lot (like 4 years or college worth).
Don't fuck around with stuff you don't know about. It's how hillbillies end up blowing up their garages cooking meth.
Don't just ask someone how it's made; educate yourself.
and don't be an idiot, for fuck's sake, we have too many these days already.
Take an organic chemistry class. Actually, take a lot (like 4 years or college worth).
Don't fuck around with stuff you don't know about. It's how hillbillies end up blowing up their garages cooking meth.
Don't just ask someone how it's made; educate yourself.
and don't be an idiot, for fuck's sake, we have too many these days already.
http://www.foodnetwork.com/recipes/rachael-ray/cracked-corn-and-cheese-squares-recipe/index.html
[youtube]KtqUe7FhiQg[/youtube]
[youtube]KtqUe7FhiQg[/youtube]
If you're looking for how things are synthesized, but not expecting to understand most of it, check out PiHKAL and TiHKAL. The syntheses are complicated but his comments about the effects are interesting, as they are often the first ever trip report on a particular substance.