History of Cannabis and the Endocannabinoid System


Well-Known Member
This article retraces the story of cannabis from the earliest contacts of humans with the plant to its subsequent global expansion, its medicinal uses, and the discovery of the endocannabinoid system in the 20th century ...
(Big Gap of Good Shit)
...Although considered a congener of heroin by the 1961 UN Single Convention, cannabis naturally belongs to the class of substances such as tobacco, alcohol, and caffeine, which are used regularly by all humanity. It might have less somatic toxicity than alcohol and tobacco. A risk of marijuana is the induction of psychosis or cognitive deficits when consumed during the neurodevelopmental period. Mechoulam’s milestone discovery that Δ 9 -THC is the primary psychoactive principle, and the ensuing elucidation of the ECS, opened the gate for a new era in cannabis history.

HERE: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605027/pdf/DialoguesClinNeurosci-22-223.pdf

Some great stuff in this short review some from current weed authors , Robert Clarke and R? Mechoulam