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Antagonism: High levels of a particular nutrient in the soil can interfere with the availability and uptake of other nutrients. For example, high nitrogen levels can reduce the availability of boron, potash and copper; high phosphate levels can influence the uptake of iron, calcium, potash, copper and zinc; high potash levels can reduce the availability of magnesium. Thus, the application of high levels of nitrogen, phosphorus and potassium can induce plant deficiencies of other essential elements.