I have always grown fems with no problems! I have grown Nirvana, Dinafem, G13, Reserva Privada, DNA, TH seeds, Barney's Farm, Cali Connection, CH9, Connoisseur Genetics, and Emerald Triangle. Potency is more about genetics than anything else. As for size, DNA's Sour Cream was huge. Flavor and smell, I would have to go with G13's Blue OG. High, Nirvana's AK48 and DNA's Sour cream were the best.