Coronavirus treatment options and the impact on public policy

Donald is touting HCQ again, if not actually taking it and there was mention of zinc. Why is this so?

The preprint paper I posted in this thread above probably explains why, it is not proof of efficacy however, it's a small observational study similar to others that made the news and proves nothing. Other proper controlled double blinded studies that offer more solid evidence are required and there are over 40 underway, some will include the addition of zinc.

Donald fucks up everything he touches and the controversy around HCQ is no different, than the pandemic preparation, planning, response, testing, treatments and now vaccines. He turned HCQ from just another drug doctors were trying and scientists were looking at, into a political red hot potato and made rational discussion of it difficult if not impossible. Donald's dangerous touting of this drug has led to a 47 times increase in HCQ prescriptions and irresponsible acts by politicians and major news networks. Patients who suffer from other illnesses need this drug and it is difficult for some to obtain it. Donald is a desperate sociopath and his latest touting might simply be a distraction from other news, many people don't believe he's actually taking it, more hope he is, takes a heart attack and dies! A victim of unwise self experimentation and pseudoscience, in short, he ate his own shit and died.

See what I mean... Donald says a stupid lie and reality has to distort itself into a pretzel shape to conform to it. Donald will have ya fired at the drop of a pin and is going through IGs like shit through a goose, he's corrupted everything including the FDA, CDC and NIH, all of their information is suspect and not to be trusted. I doubt this this decision was data driven, it was most likely Donald driven.
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FDA appears to soften stance on hydroxychloroquine after Trump says he takes malaria drug

The U.S. Food and Drug Administration said Tuesday that taking hydroxychloroquine is “ultimately” a choice between patients and their health-care providers, appearing to soften its earlier advisory against taking the anti-malaria drug outside of a hospital.

“The decision to take any drug is ultimately a decision between a patient and their doctor,” FDA Commissioner Dr. Stephen Hahn said in a statement to CNBC. “Hydroxychloroquine and chloroquine are already FDA-approved for treating malaria, lupus, and rheumatoid arthritis.”

The comments came a day after President Donald Trump said he has been taking hydroxychloroquine daily for over a week to prevent infection from the coronavirus. He said he asked his White House physician about the drug. “I asked him, ‘What do you think?’ He said, ‘Well, if you’d like it.’ I said, ‘Yeah, I’d like it. I’d like to take it.’”

However, in a warning issued last month, the FDA advised consumers against taking drugs chloroquine and hydroxychloroquine for Covid-19 outside a hospital or formal clinical trial due to the risk of “serious heart rhythm problems.”

“Hydroxychloroquine and chloroquine can cause abnormal heart rhythms such as QT interval prolongation and a dangerously rapid heart rate called ventricular tachycardia,” the agency wrote in the notice. “We will continue to investigate risks associated with the use of hydroxychloroquine and chloroquine for COVID-19 and communicate publicly when we have more information.”

If a health-care professional is considering use of hydroxychloroquine for Covid-19, they should check for a suitable clinical trial and consider enrolling the patient, the FDA said at the time.

Hydroxychloroquine, which has been repeatedly touted by Trump as a potential game-changer in fighting the coronavirus, is also often used by doctors to treat rheumatoid arthritis and lupus. Numerous clinical trials are looking to see if it’s effective in fighting the coronavirus, but it has not been formally approved for Covid-19.
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What Does Blood Plasma Therapy Mean for COVID-19?

There’s some exciting preliminary evidence that something called “blood plasma therapy” might be an option when it comes to treating COVID-19—but what exactly is blood plasma therapy and how sure we we that it will work?

A national initiative called the Expanded Access Program has been jump started by Dr. Michael Joyner and his team in order to help determine where exactly plasma therapy fits into the current COVID-19 pandemic. If Dr. Joyner and his team can prove plasma therapy works for COVID-19, it could be a viable option to control the virus’ spread We spoke with Dr. Joyner to hear more about the research his team is doing and to learn more about how blood plasma therapy works and what it could not only mean for treating COVID-19 but also future pandemics.

Maybe he will die eating his own shit!
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Hayes On Use Of Unproven COVID-19 Drug | All In | MSNBC

Chris Hayes: “The notion that the President is taking [hydroxychloroquine] speaks not only to his past, but also to the way he has gone about this entire catastrophe more broadly. Always looking for the easy solution, the magic pill.” Aired on 05/19/2020.

captainmorgan said:

Woman with lupus took hydroxychloroquine for 19 years, still got COVID-19

An Oconomowoc woman is warning people that the anti-malarial drug, hydroxychloroquine, will not protect someone from COVID-19

www.wisn.com

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I notice she was given plasma to help her recover. Anecdotes about HCQ not working are about as valuable as those that say it is a miracle cure, in scientific terms, of no value at all, ditto for the plasma she received. I personally think HCQ will do nothing for you unless you supplement it with zinc and even then the effects don't appear to be large, the jury is still out on it, but I'm not too optimistic about it, it might be used in poor countries if it has any efficacy at all, we await the proper studies. If Donald is taking this shit with his heart issues he is a fool, but that is a foregone conclusion, with any luck he might end up a dead fool.

Like I've been saying, zinc is important at a cellular level to retard virus reproduction.

captainmorgan said:

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults

This study compares angiotensin-converting enzyme 2 (ACE2) gene expression, which has been associated with SARS-CoV-2 cell entry, in the nasal epithelium of children vs adults.

jamanetwork.com

Nasal ACE2 Levels and COVID-19 in Children

Coronavirus disease 2019 (COVID-19) has disproportionately affected certain vulnerable populations. Studies noted higher rates of certain comorbidities such as hypertension, diabetes mellitus, and chronic obstructive pulmonary disease in patients infected with COVID-19 with severe disease.1...

jamanetwork.com

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Interesting, I wonder if nasal ACE2 receptor populations in adults could predict vulnerability, probably a pain in the ass to find out for practical use. Does vitamin D have an effect on the levels of ACE2 expression? Hypertension drugs increase the pulmonary ACE2 counts and this supposedly makes people more vulnerable, chronic vitamin D deficiency is also linked to hypertension by correlation studies.

captainmorgan said:

Like I've been saying, zinc is important at a cellular level to retard virus reproduction.

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As long as ya can get it inside the cells with a zinc ionophore, it might do some good, quercetin is the only legal supplement I know of that does this.

The scientific article I read about zinc and virus reproduction said it was part of natural cellular defense mechanism and people with zinc deficiencies had higher viral reproduction rates, don't remember it going into how to raise ones level.

captainmorgan said:

New York's coronavirus data sheds new light on the most severe cases: 40% died within 15 days of going to the hospital, and 67% were men

One in five New Yorkers who have been hospitalized with the coronavirus became critically ill. Nearly 40% stay in the ICU for at least a month.

www.businessinsider.com

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The thing about obese people is body fat absorbs stores and delutes vitamin D, resulting in lower serum levels, also obesity interferes with photosynthesizing vitamin D and makes production similar to the elderly who also don't produce much. The obese generally require higher supplementation levels to maintain serum vitamin D levels. Anybody carrying extra weight should endeavor to lose it and get tested for vitamin D serum levels by their doctor and keep in the high normal range, IMHO.

Maybe it's dependent on which form of zinc you take as a supplement, I always look at bio availability of the different sources.

captainmorgan said:

The scientific article I read about zinc and virus reproduction said it was part of natural cellular defense mechanism and people with zinc deficiencies had higher viral reproduction rates, don't remember it going into how to raise ones level.

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Yep it is, elevated intracellular levels, might even help fight viruses, they do in vitro, it has yet to be proven in vivo.

I actually got a email this morning notifying me that Quercetin was back in stock where I get my supplements, think I'll go order it now.

captainmorgan said:

Maybe it's dependent on which form of zinc you take as a supplement, I always look at bio availability of the different sources.

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Dunno much about zinc, I bought some zinc and vitamin C lozenges awhile back and take them infrequently. I had encounters with the health and nutrition world while strength training and have a lot of healthy skepticism, it's Trump world there and con men abound. The youth and live forever business is much the same with impossible claims.

captainmorgan said:

I actually got a email this morning notifying me that Quercetin was back in stock where I get my supplements, think I'll go order it now.

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I don't believe it has any risk associated with it, but some homework would be advised.

DIY-HP-LED said:

I don't believe it has any risk associated with it, but some homework would be advised.

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Also natural products are not regulated and ya don't know what you are getting, consumer labs might be a good place to look too for independent testing.

I took my first prescription capsule of 50000 unit vitamin D yesterday. One a week for 8 weeks and then I get my blood tested again to see where my level is at . It’s a pretty emerald green gel capsule. She also has me taking 1000 mcg of B12. Looking forward to feeling better soon.